A study led by A. M. MalfaitR. Gallily, P. F. SumariwallaA. S. Malik*,E. AndreakosR.Mechoulam, and M. Feldmann was conducted on the effect of Cannabidiol (CBD) a non-psychoactive component of cannabis on collagen induced arthritis in mice. The CBD was purified from Hashish and the mice were administered with differing doses of the extract through injection or they were given an oral dose. The study concluded that the anti-inflammatory effect was insignificant, however, histological evaluation showed protection of joints.

For further reading on this study please visit:


A study led by D. R. Blake, P. Robson, M. Ho, R. W. Jubb and C. S. McCabe in 2005 was conducted on the effect of Sativex a cannabis based medicine on the treatment of pain from Rheumatoid Arthritis. 58 patients were used in the study where 31 were being treated with Sativex which was administered in an oral spray and 27 were given a placebo. Patients who were treated with Sativex were reported to have statistically significant improvements in pain on movement, pain at rest, and quality of movement. Side effects were very moderate and ranged from light headedness, dizziness, and dry mouth. There was no effect reported on improvement on morning stiffness. The conclusion showed benefits of clinical significance of the analgesic effect of Sativex on arthritis and suggest the need for more detailed research.

For further reading on this study please visit: