Huntington’s Disease Marijuana Studies

WSJ Team September 17, 2010 6

A study led by Reuven Sandyk, Paul Consroe, Lawrence Z. Stern, and Stuart R. Snider was conducted to see the effect of Cannabidiol a non-psychotropic drug on 3 patients who have been suffering from Huntington’s disease for 7 to 12 years. The subjects were given a 300 mg/dose that was orally administered for the 1st week and then increased to 600mg/dose for the remaining 3 weeks. It was observed that choreic movements were improved by 5 to 15% during the first week using the tongue protrusion test and a chorea severity evaluation scale. There was an additional improvement of 20 to 40% after the second week of CBD treatment and it remained stable for the remaining 2 weeks. When the patients stopped the CBD treatment after 48 hours the choreic movement returned to their original state.

For further reading on this study please visit:

A follow up study led by Consroe PLaguna JAllender JSnider SStern LSandyk RKennedy KSchram K, was conducted to see the effect of Cannabidiol in patients with Huntington’s Disease based on the results in the previous study. The study was conducted on 15 neuroleptic-free patients with Huntington’s disease were given doses of CBD or a sesame oil placebo. After 6 weeks of CBD administration there was no significant difference in therapeutic outcome variables with the placebo. It was concluded that CBD was ineffective and non-toxic for the treatment of Huntington’s disease relative to the placebo.

For further reading on this study please visit:


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  3. chris murrey July 21, 2012 at 6:57 PM - Reply

    hey guys, my mum suffers from HD, i think its quite far progressed, hard to tell!!! shes on all sorts of shitty drugs which are designed to numb the movements. i would like to get her off the mind numbing drugs which are legal!!! and get her on to something natural!!! i am going to try some homegrown weed. How much should i put in a spliff do you guys think? This is a honest question, i am really looking for something else. Any help is greatly appreciated. Thanks

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