A large and extensive study was led and sponsored by Kaiser Permanente in San Francisco, California. The study observed 65171 men and women aged between 15 and 49 years old over an average time period of 10 years in order to evaluate whether marijuana use affects the mortality of men and women. Current Marijuana smoking was defined by admission to smoking currently and more than 6 times ever. Former marijuana smoker were defined by admitting to smoking more than 6 times but are in denial of smoking currently, experimenters admitted to smoking between 1 and 6 times, and non-smokers were defined as never having smoked. The subjects that were part of this study underwent multiphase health checkups. Mortality was assessed by using Kaiser Permanente membership file records and for subjects who were no longer members the researchers used California Automated Mortality Linkage, and CAMLIS an information system. For those subjects who left the state Mortality was assessed using Social Security numbers and linking them to a Pension Benefits Information database that includes mortality data from the State of California Center for Health Statistics. Among the subjects in this study there were 807 male deaths and 408 female deaths. According to this study marijuana use in men increased the risk of total mortality. The risk increase is explained as a strong relationship between marijuana use and AIDS mortality. The risk however in non-AIDS mortality and marijuana use there was no association between mortality and marijuana use. In women there was no increased risk in mortality as a result of marijuana use.

For further reading on this article please visit: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1380837/pdf/amjph00503-0059.pdf