Sleep Apnea Marijuana Studies

WSJ Team September 17, 2010 2

A study led by researchers the University of Illinois at the Center for Sleep and Ventilator Disorders was conducted to observe the effect of THC on sleep, respiratory pattern, and sleep apnea in rats. The study was conducted on 11 rats who expressed sleep apnea. The rats were injected with various doses of THC, oleamide, and serotonin, alone and in combination. The data showed that THC and oleamide stabilized respiration during all sleep stages. The oleamide and THC would inhibit serotonin induced sleep apnea. The researchers concluded that cannabinoids can suppress sleep apnea and are extremely important to contributing to pharmacological research for treatment of sleep related breathing disorders.

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  1. yuli June 17, 2012 at 11:56 PM - Reply

    WHY would cannabis help sleep apena? WHAT receptors does it touch? What is the mechanism of action that would help people with sleep apnea? And of course cannabis has zilcho effect on an enlarged tonsil or tongue so in the absence of repairing a mechanical defect, hello, smoking a dubie ain’t going to solve it. Nice try. But do agree it probably is safer than taking sleeping pills for insomnia, so if cannabis replaces xanax, ambien, clonazepam or valium, then yeah, I can see that working better since now the person isn’t all doped up on benzos and have a hard time breathing.

    • Levi April 13, 2013 at 8:00 PM - Reply

      Cannabis contains compounds named cannabinoids which are mainly agonist of the cannabinoid receptors, CB1 and CB2. Some cannabinoids, like THC, can dialate the bronchial tubes in the lungs and increase the amount of absorbtion of oxygen. But in this study, cannabinoids were also found to regulate breathing patterns, as well as control serotonin based apnea. There has been no follow up study, only the study on rats, then humans. But thats about all I know why

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